All time powerful female characters in Anime 

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Kaguya Otsutsuki (Naruto) Kaguya Otsutsuki, the supreme celestial entity from the Naruto universe, first used chakra and subsequently changed into the Ten-Tails.

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Tatsumaki (One Punch Man) The S-Class Rank 2 professional hero in the Hero Association, Tatsumaki, is one of the godlike heroes on One Punch Man's roster.

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Kale (Dragon Ball Super) By far the strongest female character in Dragon Ball Super is Kale, a pure-blooded Saiyan. Even some of the show's fiercest male characters can't stand a chance against her.

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Merlin (Seven Deadly Sins) This character is portrayed in Seven Deadly Sins in a very distorted way compared to Merlin in the Camelot myth. She is a mystery person who gradually manifests her divine ability.

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 Erza Scarlet (Fairy Tail) Erza is a Fairy Tail Guild S-Class Mage and a member of Team Natsu. She is an expert in hand-to-hand combat, archery, and swordplay.

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Akame ga Kill (Akame ga Kill) The fiercest member of the band Night Raid is Akame, the title character of Akame ga Kill.

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 Izumi Curtis (Fullmetal Alchemist) Izumi is a skilled martial artist and alchemist. She possesses one of the strongest bodies of any character in the series and is incredibly skilled in hand-to-hand fighting.

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 Misa Amane (Death Note) Misa Amane lacks any knowledge of magic or battle experience. Her strength derives instead from her fervour, wit, and of course, her Death Note.

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