Prince Frederik, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, passed away at the age of 22. He died from a rare genetic disease, POLG Mitochondrial disease, announced the Royal family on Sunday. Frederik passed on March 1, in Paris. The Royal family wrote, “Frederik passed on March 1st 2025, in Paris France, the City of Lights. One light was extinguished, but so many remain.” Frederik was diagnosed with POLG at the age of 14.
Who Was Prince Frederik?
Prince Frederik was the POLG Foundation Founder and Creative Director. He was born on 18 March 2002. His family regarded him as the ‘strongest’ person that they knew. Frederik saw the beauty in everything.
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Born in Aix-en-Provence, Frederik spent his first two years living in London England, before moving to Geneva, Switzerland in 2004 and eventually to Vevey and Montreux. He attended the International School in Geneva. Frederik later attended St George’s School, in Clarens.
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His passions included: Music, Film, Television, Gastronomy, Nature, Fossils and Minerals, Photography and Art. He had watched the American adapted tv show The Office, in its entirety, over 10 times. The youngest Prince loved his home in Switzerland.
Frederik was diagnosed with POLG at the age of 14. He was also interested to help the science move forward. “He actively and literally gave of himself to develop multiple mouse models and cell lines in Switzerland, the United States, and Europe and to make these available to further facilitate research into POLG,” stated the Royal family through POLG Foundation website. He launched the MITO clothing line.
Frederik voiced his gratitude for having the disease, stated the Royal Family. “I am glad that I am the one who was born with this disease. Even though I’ll die from it….and even if my parents do not have the time to save me, I know that they will be able to save other children,” told Frederik to Andrew.
According to the Royal Family, Frederik had called all his family members to his room to say goodbye on February 28. “Last Friday, February 28th, on “Rare Disease Day”, our beloved son called us in to his room to speak to him for one last time. Frederik found the strength and the courage to say goodbye to each of us in turn – his brother, Alexander; his sister, Charlotte; me; his three cousins, Charly, Louis, and Donall; his brother-in-law, Mansour; and finally, his Aunt Charlotte and Uncle Mark,” stated the Royal Family.
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